Cells for New life

Fetal Stem Cells

EmProCell Fetal Stem Cells Technology

Fertilization of the oocyte initiates a series of events following gastrulation, during which pluripotent stem cells progressively lose potential as the early embryo is patterned along its axes and organ structures are specified. Tissue-specific programs subsequently direct the formation and maturation of fetal and adult organs, which are maintained throughout life by stem cells with tissue-restricted lineage potential.

The development program of fetal progenitor cells is clearly determined by the formation of the tissue cells of completely specific kind like heart, muscle, kidney, lung cells, etc. This means that after the separation of cells and their administration to the patient, progenitor cells will continue differentiating only to the specified type of tissue programmed by cellular development. For example, in Hepatic cirrhosis, liver progenitor cells are used. These cells are able to differentiate only into hepatocytes in future.

Important Aspects Of Fetal Progenitor Cells:

  • Fetal progenitor cell do not require additional manipulation associated with the expansion and directed differentiation since they may easily be separated in large quantities and they are already digested by the formation of a specific type of tissue, that  means they are ready for use after separation.
  • Biologically Fetal progenitor cells cannot be the source of cancer cells since they are not stem cells.
  • A unique property of fetal progenitor cells is their ability to penetrate the histo-haematic barriers including the blood-placental barrier into the mother’s blood. They circulate in first trimester fetal blood and have been found to traffic into the maternal circulation, engrafting in bone marrow, where they remain microchimeric for decades after pregnancy. 
  • They are able to induce immune tolerance to themselves! This means that after administration of the fetal stem cells they are not rejected by the patient’s immune system, but they easily survive and perform its function: to replace the diseased tissue of the patient’s body.